Choose your plates from our available cancer cell lines
The Cell2Sphere™ product kit includes three elements:
- A standard 96 well plastic plate that can be directly used in existing drug screening platforms.
- CSC enriched single cells in each well, the laboratory can add any compounds to be analyzed to the well.
- A proprietary culture medium.
The mixture indicates the efficacy of the compound against spheroid growth, while letting researchers determine spheroid formation on existing imaging platforms. It is also possible to test for health of 3D spheroids using conventional viability assays (such as Cell-Titter Glow® from Promega or MTS® viability assay from Sigma). More cancer cell lines to come soon:
|KITS||CELL LINE||TUMOR TYPE||FEATURES|
|BREAST||MDA-MB-436||TNBC||ER-/PR-/HER2- BRCA1 mut/PTEN mut|
|BT474||Luminal B||ER+/HER2+ p53 mut/PI3KCA mut|
|OVARIAN||OVCAR-3||Epitehlial Adenocarcinoma||AR+/ER+/PR+, Platinum resistant|
|SK-OV-3||Epithelial Adenocarcinoma||Platinum resistant|
|PROSTATE||DU-145||Epithelial Carcinoma||PSA-, hormone resistant|
1. Your order will be shipped frozen. It is storable.
2. Apply culture medium.
3. 37oC / 6 days.
4. Ready to use.
Get a phenotypic readout of CSC function (spheroid formation), and viability assay in 3D using conventional laboratory equipment.
Standard 96 well plates allows for direct integration to existing drug screening platforms.
Plates are delivered frozen for long term storage and convenience, ideal for flexible experimental planning.
NO TRAINING NEEDED.
Anybody can perform 3D cell culture assays using the Cell2Sphere™ kit. Only minimal experience required in manipulating conventional tissue culture material.
Cell2Sphere™ Product Line
A unique ready-to-use solution for 3D drug compound screening.
Choose your plates from our available cancer cell lines.
Mix and match your own plate with our available cancer cell lines.
Use your own cancer cell lines to customize and create your own Cell2sphere™KITS